Cboe Canada GDAI · FWB ZN0

Company

Founded by the people who kept seeing it missed.

GuideAI Health was established by clinicians to close a gap they encountered in practice: early peripheral arterial disease sitting unread in imaging acquired for another reason.

Origin

A pattern, then a model.

Dr. Raj Shah and Dr. Luke Higgins — both interventional radiologists — kept encountering the same thing: patients arriving with advanced peripheral arterial disease whose earlier imaging, taken for something else entirely, had already contained the signs.

They began developing computer-vision models to detect vascular markers in that existing imaging. Dr. Amin Katouzian joined to scale the AI infrastructure and carry the work through regulatory readiness.

The mission has not changed since: enable earlier intervention, before disease becomes irreversible. That means detecting PAD markers before symptoms appear, reducing adverse cardiovascular events, and delivering insight that is actionable without disrupting the radiology workflow it arrives in.

Milestones

Four years, clinical genesis to clearance.

— 2022–2023Clinical genesis Founded by practising interventional radiologists. First computer-vision models developed for vascular marker detection in existing imaging. Founding
— 2024Into the clinic Clinical pilots launched. Named a Company to Watch at the LSI Emerging Medtech Summit. Pilots
— 2025Recognition and availability Featured in Canada’s Drug Agency Horizon Scan. Commercial availability begins. Commercial
— 2026Clearance and listing FDA 510(k) clearance for VascularAssist Occlusion Triage, with above 90% patient-level sensitivity reported in validation. Listed on Cboe Canada (GDAI) and the Frankfurt Stock Exchange (ZN0). Cleared

Leadership

The people accountable for it.

Raj Shah, MD MBA, Chief Executive Officer

Raj Shah, MD MBA

Chief Executive Officer

Interventional Radiologist · Miami Cardiac & Vascular Institute · U of Connecticut

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Dr. Raj Shah is a physician-executive and operator focused on building and scaling healthcare technology platforms. As CEO of GuideAI Health, he leads the company’s strategy, commercialization, and execution as it brings Elevate—a clinical workflow platform that transforms imaging insights into coordinated patient care—to market.

With training in both medicine and business, Dr. Shah has experience across clinical operations, digital health, and care delivery innovation. He has led initiatives that integrate technology into real-world clinical workflows, with a focus on driving adoption, improving outcomes, and aligning with sustainable revenue models.

At GuideAI, he is responsible for productization, health system partnerships, regulatory strategy, and go-to-market execution. He works closely with clinical, engineering, and industry partners to build a scalable platform that enables earlier disease detection, standardized reporting, and efficient care coordination across large patient populations.

Luke Higgins, MD PhD, Chief Medical Officer & Chief Operating Officer

Luke Higgins, MD PhD

Chief Medical Officer & Chief Operating Officer

Interventional Radiologist · Stanford · Johns Hopkins · Brigham and Women’s Hospital · MIT

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Dr. Luke Higgins is a physician-scientist and interventional radiologist who has built his career at the intersection of clinical medicine, innovation, and system-level change. Across training at MIT, Johns Hopkins, and Stanford, and clinical practice within leading health systems, he repeatedly encountered a fundamental problem: modern healthcare excels at detecting disease—but fails to act on it.

He founded GuideAI Health to solve that gap.

As the originator of the Elevate platform and the “hospital engine” concept, Dr. Higgins is leading the development of a new category of healthcare infrastructure—one that transforms imaging findings into coordinated, longitudinal care pathways for patients with chronic PAD. His work is grounded in both scientific rigor, with publications in Nature, and real-world clinical insight from treating complex PAD across diverse care settings.

Dr. Higgins’ vision is to move healthcare from reactive intervention to proactive disease management—unlocking the full value of AI in medicine by ensuring that every detected disease leads to meaningful clinical action.

Amin Katouzian, PhD, Chief Technology Officer

Amin Katouzian, PhD

Chief Technology Officer

IBM Watson Health · 20+ patents · Columbia PhD · PI-CAI Grand Challenge winner

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Dr. Amin Katouzian is an AI scientist and technical leader specializing in machine learning and medical imaging. At GuideAI Health, he has led the development of core algorithms for PAD detection, including early work on PAD models and occlusion detection.

Dr. Katouzian previously held roles at IBM Watson Health, where he worked on applying artificial intelligence to complex healthcare datasets and clinical use cases. His expertise spans computer vision, deep learning, and the development of AI systems for medical applications.

At GuideAI, his work has focused on building and validating disease detection models, including contributions toward early regulatory efforts such as FDA clearance for occlusion detection. He has been instrumental in establishing the company’s foundational AI capabilities and technical infrastructure for imaging-based analysis.

His role centers on advancing GuideAI’s AI research and development efforts, including model design, training pipelines, and performance optimization, as the company continues to expand its capabilities in imaging-based disease detection.

Management: Paul More (CFO) · Tasheel Jeerh (President)

Scientific, clinical & advisory

Evidence, methodology and counsel.

Omid Sakhi, Lead AI Scientist

Omid Sakhi

Lead AI Scientist

A lead AI scientist building scalable medical imaging solutions for real-world clinical use.

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Omid Sakhi is an AI scientist and technical leader specializing in the development of machine learning models for medical imaging and clinical applications. As Lead AI Scientist at GuideAI Health, he is responsible for designing, training, and deploying the core algorithms that power the Elevate platform.

Omid brings deep expertise in computer vision, model development, and data-centric AI, with a focus on translating complex clinical problems into scalable technical solutions. His work spans model architecture design, annotation strategy, performance optimization, and real-world deployment—ensuring that GuideAI’s AI systems are both technically robust and clinically meaningful.

At GuideAI, he leads the development of imaging-based models for PAD detection and characterization, working closely with clinical and engineering teams to build end-to-end pipelines from raw imaging data to structured, actionable outputs. He plays a central role in transforming annotated datasets into production-grade models that integrate directly into clinical workflows.

Omid is particularly focused on bridging the gap between research-grade AI and deployable healthcare systems—optimizing models not just for accuracy, but for reliability, scalability, and real-world clinical impact.

Kourosh Jafari-Khouzani, PhD, Lead Data Scientist

Kourosh Jafari-Khouzani, PhD

Lead Data Scientist

IBM Watson Health · iCAD

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Dr. Kourosh Jafari-Khouzani is an expert in medical imaging and computational neuroscience. With an extensive background in developing automated tools for MRI and CT analysis, Kourosh translates complex clinical data into actionable AI models. His work at GuideAI focuses on refining the computer vision layers that identify early-stage vascular markers often overlooked in standard reviews.

James Benenati MD, Clinical Advisor

James Benenati MD

Clinical Advisor

Interventional Radiologist · Chief Medical Officer, Penumbra · Miami Cardiac & Vascular Institute

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Dr. James F. Benenati is a nationally recognized leader in interventional radiology and a pioneer in advancing minimally invasive, image-guided therapies for vascular disease. He currently serves as Medical Director at the Miami Cardiac & Vascular Institute, part of Baptist Health South Florida, one of the premier cardiovascular programs in the United States.

With decades of clinical experience, Dr. Benenati has been at the forefront of innovation in PAD, endovascular therapy, and complex vascular interventions. He has played a central role in shaping modern vascular care pathways, emphasizing multidisciplinary collaboration, procedural excellence, and patient-centered outcomes.

Dr. Benenati is also a respected educator and thought leader, having trained numerous physicians and contributed extensively to clinical research and professional societies. His work has helped define best practices in interventional radiology and elevate standards for quality and safety across the field.

As an Industry Advisor to GuideAI, Dr. Benenati provides strategic clinical insight to support the development and adoption of the Elevate platform. His expertise ensures that GuideAI’s solutions align with real-world physician workflows, address critical gaps in vascular disease management, and deliver meaningful improvements in patient care and health system performance.

Alok Gupta, Advisor

Alok Gupta

Advisor

Healthcare & AI Executive · Wharton MBA · UPenn PhD AI & Computer Vision

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Alok Gupta is a global healthcare and AI senior executive who has served as general manager, CEO and president across health technology, payer and provider health IT, medical devices and medical AI, including imaging, machine learning and natural language processing. He is known for bringing innovative products to market, building new businesses and developing high-performance teams.

As General Manager and VP of Merge Imaging (IBM Watson Health, now Merative), he led the $200M imaging business and its 900 employees and contractors through the transition to a stand-alone, PE-owned company. Earlier, as VP of R&D at IBM Watson Health for Imaging, Oncology and Genomics, he led a global team of more than 500 developing enterprise-grade, cloud-enabled, FDA-regulated medical imaging products.

At Siemens Healthcare he founded and built a new business to develop and commercialize AI-based computer-aided diagnosis and predictive analytics applications through the 510(k), PMA and CE regulatory pathways, and he led the Siemens Research global R&D center in image processing, computer vision and machine learning. He has also served as COO and CIO of the Rhode Island Quality Institute, SVP and CIO of CareFirst BlueCross BlueShield, and Executive VP and CTO of ikaSystems.

He holds an MBA from The Wharton School, a PhD and MSE in Computer and Information Science, specializing in artificial intelligence and computer vision, from the University of Pennsylvania, and a B.Tech in Computer Science and Engineering from the Indian Institute of Technology (IIT), Kharagpur.

How we talk about what we have

Name the indication, and stop there. The indication is the boundary.

Internal standard for every claim we make

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Clinical partnerships, channel relationships, and the roles we are hiring for — all start at the same address.